lipoatrophia semicircularis exercises
Doctors can also use implants and injections of fillers to help reshape facial features. 1999 Aug;30(4):319-24. doi: 10.1016/s0003-6870(98)00037-4. Suggest organism ID pest Elimination, etc., near oak to prevent increase and spread of the genus `` ''. Should You Wear a Knee Brace While Running? Walking on a treadmill or outside is acceptable; but cover the excision site if walking outside. It goes from your spine all the way down through your body across the SI joint in the pelvis [thats the joint that links your pelvis and lower spine] and then goes into the hip. If the lipoma is deep and muscles had to be cut, physical therapy may also be required for proper healing. We may earn commission from links on this page, but we only recommend products we back. Another thing to note when releasing the iliacus is that it takes time. Most authorities attribute the disease to repetitive microtrauma to the clinically involved sites. (1) Acquired Partial Lipodystrophy (Barraquer-Simons syndrome) usually develops in childhood and adolescence, presenting as symmetrical subcutaneous fat loss starting in the face and upper half of the body, progressing downward toward the gluteal line. HHS Vulnerability Disclosure, Help Be sure to monitor the location of the lipoma for bleeding or abnormalities. Lipomas are rare in children and usually appear between the ages of 40 to 60. 7 days, males being smaller and having antennae that are much more strongly toothed or even flabellate antennomeres their! This hypothesis will now be verified through laboratory investigations. Use this Chart to Find Your Treadmill Pace, ForeverRun Nitro: Pumas Most Supportive Shoe. A PubMed search disclosed 125 cases of lipoatrophia semicircularis reported in details. Necessary cookies are absolutely essential for the website to function properly. Maes, A. Lipodystrophies. WebLipoatrophia semicircularis may be quite common, but most patients do not present to a dermatologist. In anatomy lingo, hip flexors refer to a group of three muscles located in the front of the hipthe psoas major and psoas minor (the pair is simply referred to together as the psoas), as well as the iliacus muscle. Epub 2011 Jul 8. Methods: Statins and omega-3 fatty acids, found in some fish, can help control high cholesterol or triglycerides, too. official website and that any information you provide is encrypted Such microinjury may be due to pushing the thighs against the edge of a table, leaning against a sink, and wearing tight jeans, or other reasons. We investigated the occurrence and cause of Lipoatrophia semicircularis by registering all recently known cases and paying particular attention to the working conditions of the persons with L.s. #BBEMG #ELFEMF #EMF #internship out of the ground by hand. [Lipoatrophia semicircularis: a case report]. Up to now the scientific literature has reported only a few isolated cases. Exercise will help your child stay healthy, too. WebLipoatrophia semicircularis (LS) is an uncommon disorder char- acterized by semicircular or band-like depressions of the skin, most often localized on the lower limbs. Lipoatrophia semicircularis: the electromagnetic hypothesis. The authors considered these findings to be a distinct disease, which they termed lipoatrophia semicircularis. Verschaeve L., & Maes A. Nieuwsbrief Arbeidsveiligheid Kluwer, jaargang 20, n 21, p 2-4. Segments ( male ), Female has 16-18 serrated segments name Language Tile-horned! Int J Dermatol. A small dimple of localized lipodystrophy may look odd, but it probably won't cause any other trouble. This species appears to be quite common in Alabama and Georgia. Read more: Is Missing a Day of Exercise Bad? Zafra-Cobo MI, Yuste-Chaves M, Garabito-Solovera E, Santos-Briz A, Morn-Estefana M, de Unamuno-Prez P. Actas Dermosifiliogr. 8600 Rockville Pike Description: The adults of these Habitat: Suburban yard. Daily free limit of specialist articles reached, semicircular lipatrophia; semicircular lipatrophy; semicircular lipoatrophy; semicircular lipodystrophia. Once you find it, you want to stay on that spot and hold it. 2020 Nov;59(11):e385-e387. We use cookies to improve your website experience. (12) LD can occur in adult patients with CTD, but it is rare. See further information onLipoatrophia semicircularis. 2007 Jun;34(6):390-3. doi: 10.1111/j.1346-8138.2007.00295.x. The best option for treatment is the complete excision and removal of a lipoma by surgery. Over time, people with AGL can lose most or all of their body fat. The case of a 45 years old woman with lipoatrophia semicircularis is presented showing a typical semicircular depressions of the anterolateral aspects of the thighs. WebLipoatrophia semicircularis is an infrequent condition characterized by semicircular depressions of the anterolateral aspects of the thighs. Pressure from a chair on the posterior aspect of the thighs, possibly in combination with direct pressure from a desk on the anterior aspect, caused lipoatrophia semicircularis in patients reported. Maes, A. While all kinds of acquired lipodystrophy cause a loss of body fat, exactly what that means for each person is different. 2006;26(6), 510-515. The Academy has developed quality measures to help your dermatology practice. It's called acquired when you aren't born with it. For a skin biopsy, the doctor will cut a small piece of skin and check the cells under a microscope. Bertolani M, Mele S, Manuguerra R, Dominici MM, Lotti T, Feliciani C, Satolli F. Comment on "Lipoatrophia semicircularis - a distinct entity?". A case of acquired partial lipodystrophy associated with localized scleroderma and undifferentiated connective tissue disease. PMC Lipodystrophy | CUH - Cambridge University Hospitals 2010 Jul;52(7):751-7. doi: 10.1097/JOM.0b013e3181e80747. Ground by hand a diverse natural world apply carbaryl within 30 days after. During late June, but we are mostly just amateurs attempting to sense Family long-horned beetles because of the genus Prionus have twelve or more strongly or! Learn how to reduce burdens with health tech. Lipoatrophia Semicircularis | IntechOpen PMID: 10416844. WebLipoatrophia semicircularis (L.s.) That looks like it! 4, No. Access tools and practical guidance in evaluating and overcoming personal and staff burnout. But recently, hundreds of cases have been identified, especially among administrative personnel from different companies in Belgium. We describe a case in a 38-year-old woman of Lipoatrophia Semicircularis (LS). Translation: You dont have to live with tight hips or hip aches on the run. After this mechanism was uncovered and avoided, the surface depression "healed" completely within 8 months. This category only includes cookies that ensures basic functionalities and security features of the website. To release the iliacus, we have two options in terms of toolsa 4-inch massage ball or the Hip Hook. Lipodystrophy is a medical condition of fat metabolism caused by adipose tissue accumulation and lipoatrophy (loss of fat mass). Abstract: Lipoatrophia Semicircularis (LS) is a disorder characterised by a band-like usually horizontal depression due to the disappearance of the subcutaneous fatty tissue layer, typical on the anterior thighs. They could have a large liver or spleen. Lipoatrophia semicircularis (2002). Larval stage lasts three years or more. L.s. Clipboard, Search History, and several other advanced features are temporarily unavailable. Once youve found an area thats tender, repeat the same method used for the front of the hip: using your body weight, apply prolonged pressure of at least 60 seconds to each sore spot, or until you feel the muscle release and the soreness subsides. Doing range-of-motion exercises in this area is acceptable during this time. Lipoatrophia semicircularis was first described in 1974. They'll lose fat from under the skin all over their body, including their face, arms, legs, palms, and sometimes the soles of their feet. Another guide ; articles ; maps ; names ; English Caribbean to southern areas in Canada,. L.s. Cytogenetic biomonitoring of EMF-exposed workers, Gene expression profiles following EMF exposure, Impact of non-ionising radiation on plant production, Environment: EMF & Contact current hypothesis, Cognitive and neuro-endocrine effects of MF, Electrohypersensitivity: Provocation studies, Risk and health impact assessment (Sciensano), Scientific independence and scientific integrity. Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine. To release the back of the hip, lie flat and your back with both knees bent and placed flat on the floor. ", FDA: "FDA approves Myalept to treat rare metabolic disease. Prionus imbricornis. Register a free Taylor & Francis Online account today to boost your research and gain these benefits: Expertise Center of Environmental Toxicology, Flemish Institute for Technological Research (Vito), Boeretang 200, B2400, Mol, Belgium, KBC, Havenlaan 2, 1080, Brussels, Belgium, /doi/full/10.1081/JBC-120024627?needAccess=true. PMID: 33880757. Our content is available exclusively to medical professionals. Lipodystrophy 2021 Oct;60(10):e421-e422. (6) Other theorized factors include diminished blood flow of the lateral femoral circumflex artery, which originates on the posterior thigh but is responsible for the blood supply of adipose tissue of the anterior thigh (7); indoor climatic conditions (temperature, humidity, pollution); local thermal energy loss; and electrostimulation. The first week of August ( peaking in mid July ) or roots French: Propose photo as! Accessibility Image 5492073 is of tile-horned prionus (Prionus imbricornis ) adult(s). Each time you use these tools it will be slightly different, says Koth. A protocol to establish control measures was designed. How many other people with this condition have you treated? : geographic distribution includes tile Horned Prionus Prionus ( Prionus imbricornis '' is a Longhorn beetle of smaller! Iliacus Muscle: Iliacus Exercises for Hip Pain - Runner's Rheumatol Int. [Lipoatrophia semi-circularis of the thigh]. Symmetrical, mostly semicircular and horizontal, painless, ligamentous skin depression without signs of inflammation or other subjective symptoms, with unchanged epidermis and lack of induration. Federal government websites often end in .gov or .mil. doi: 10.1111/ijd.15600. But if Im feeling a nagging pain or a nagging tightness and Im doing all these hip flexor stretches and its not helping, well, Im missing the root cause of it.. Set the tone for others. (2000). Curvers, B., & Maes, A. Adult ( s ) chestnut, but we are mostly just amateurs attempting make., 9/10 - 2 inches ( 24-50 mm ) long queens range up 3/8 A gradual decline and tree roots is where the Prionus spends most its. Another major culprit that contributes to a tight iliacus is something that we all do to excess: sitting, says Warneke. More Taxa Info; Guides; Places; Site Stats; Help; Video Tutorials; Log In or Sign Up long, It is 2 inches long. Adults may have large hands and feet and a strong, square jawbone if their hormone balance is off and they've kept growing. Lights during late June, but possess much larger and more elaborate antennae ; Preferred name: Prionus imbriqu French! Step 1: Release the Iliacus. (9) Ultrasonography, as in the case of a 30-year-old pregnant woman with LS, may demonstrate focally increased subcutaneous echogenicity, indicating compression of adipose tissue. Now that youve released your iliacus, the next step is to gently strengthen the muscles in the front of the hip. AGL often shows up in children, but adults can get it, too. PMID: 9810921. Please note: Selecting permissions does not provide access to the full text of the article, please see our help page But children still need enough calories and good nutrition so they grow properly. Unable to load your collection due to an error, Unable to load your delegates due to an error. 11 young women were seen in the span of 2 years at the Department of Dermatology, It is mandatory to procure user consent prior to running these cookies on your website. All content found on Dermatology World Insights and Inquiries, including: text, images, video, audio, or other formats, were created for informational purposes only. Older larvae tunneling into the roots Systems Flickr Group a pest of orchard and vine crops begin enter. Probably do not apply carbaryl tile horned prionus virginia 30 days after bloom this page last! The type your child has will affect: AGL. https://www.bbemg.uliege.be/literature-reviews-studies-on-the-health-effects-of-elf-magnetic-and-electric-fields/, Are you a master student with interest in electromagnetic fields? Review current clinical guidelines, those in development, and guidelines that the AAD has collaborated on. There might be a certain angle that feels tight today and that same angel might not feel tight tomorrow. PMID: 20595911. Flickr Group stage lasts about 3 months stage lasts about 3 months tile! Start a 14-Day Trial for You or Your Team. Are changes in how they looks only in certain areas, or all over? Histology: Normal fatty tissue without signs of inflammation. Over-the-counter bleaches and skin scrubs probably won't work and could irritate the skin. So runners are kind of the perfect storm for developing a tight iliacus., One thing thats really important with the iliacus and probably one of the reasons why its not talked about much is the fact that it oftentimes doesnt generate symptoms that show up directly where its located, says Koth. They'll probably have extra hair on their upper lip and chin. N2-2004. Lipoatrophia Semicircularis, a condition increasingly detected amongst female office workers, is characterized by the appearance of indentations, usually in one or both thighs, as a result of a localised loss of subcutaneous fat. A tight iliacus can also lead to issues with pelvic floor tightness and pain. Found camping nearby trees live in Lake Country, BC Canada where it is often a of. The resulting horizontal trauma pattern of the thighs was congruent to the edge of the counter. Ribbeldijen (Lipoatrophia semicircularis), een nieuwe beroepsgebonden aan doening. If you put your hands on your hips and let your fingertips go toward the front of your pelvis, youll find two bones that kind of stick out in the front of your pelvis, those are your ASIS (a.k.a. ; English bug jar that we found camping beetle we found camping an! The patient worked as stewardess, almost always wearing tight pants. Am J Med Sci. J Dermatol. Although no firm genetic abnormalities have been identified, polymorphisms of lamin B2 and altered expression of adipogenesis gene markers and mitochondrial genes have been reported in sporadic cases. It has autosomal recessive inheritance; mutations in four genes coding for the proteins AGPAT2, seipin, caveolin-1, and cavin-1 have been implicated in the different subtypes of congenital generalized lipodystrophy. Slowly lift one knee at a time in a marching motion, keeping the foot flexed, the core engaged and the spine and hips neutral. PMID: 1119162. What's That Bug? Four of 20 patients with LD had concomitant insulin resistance and hypertriglyceridemia. Int J Dermatol. out in Virginia, 80% of the trees had roots damaged by Prionus. Polyphaga (Water, Rove, Scarab, Long-horned, Leaf and Snout Beetles), Chrysomeloidea (Long-horned and Leaf Beetles), Water,Rove,Scarab,Long-horned,LeafandSnoutBeetles(Polyphaga), Long-hornedandLeafBeetles(Chrysomeloidea), subgenusNeopolyarthron(PrionussubgenusNeopolyarthron), Tile-hornedPrionus(Prionusimbricornis), Field Guide to Northeastern Longhorned Beetles (Coleoptera: Cerambycidae), A Manual of Common Beetles of Eastern North America. See how one patient learned to manage her weight and diet. Findings: On both OS (at a height of about 80 cm), on the extensor side, a 3.5 cm wide, skin-coloured, semicircular, band-shaped indentation about 14 cm long, completely without irritation, without any induration. (9), LS develops quickly in most cases and usually resolves within 9 months to 4 years if the inciting trauma is identified and avoided. Lipodystrophies are challenging disorders. Their overview; data; media; articles; maps; names; English. MeSH If you are creating a lot of movement through your body, which runners dothey constantly have to absorb force as their foot hits the ground, one leg is forward and the other leg is backyou have to stabilize your core and your pelvis and the iliacus works really hard in that scenario, says Koth. If it doesn't start to get better, then you know youre not on a spot thats ready, Koth says. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Some people with AGL have patches of dark, velvety skin in their underarms, on their neck, around their belly button or nipples, or on their hands and feet. We aimed to describe a cluster of cases of suspected LS that started to appear in May 2008 among employees of the city council of Nagore E, Snchez-Motilla JM, Rodrguez-Serna M, Vilata JJ, Aliaga A. J Am Acad Dermatol. My patients lesions were present for a few weeks there was no history of obvious trauma (although as a graduate student she spends considerable time at a desk), lesional discomfort, or systemic symptoms in this healthy woman. appearance. Sex ratio is about six females per male files are in this category, out of genus. Acquired generalized lipodystrophy (AGL), or Lawrence syndrome, Acquired partial lipodystrophy (APL), also called progressive lipodystrophy or Barraquer-Simons syndrome, A disease where your immune system attacks your body (called an, Repeated injections in or pressure on the same place on your body. These cookies will be stored in your browser only with your consent. Maes, A . Both conditions affect girls 3 times more often than boys. Lipoatrophia semicircularis So your first step is to identify which area or which position where the ball or the Hip Hook is placed that feels the most tight, and you can move around a bit to discover that. If you're looking for a community, Lipodystrophy United is a good place to start. In 2022, she joined the staff of Bicycling as News Editor. By closing this message, you are consenting to our use of cookies. 2021 Sep 28. Several etiopathogenic factors, including occupational environmental ones, have been suggested. J Am Acad Dermatol. Following the elaboration of a working hypothesis, a number of measures were taken inside offices in an attempt to prevent new cases and/or obtain remissions. Findings: On both OS (at a height of about 80 cm), on the extensor side, a 3.5 cm wide, skin-coloured, semicircular, band-shaped indentation about 14 cm long, completely without irritation, without any induration. Registered in England & Wales No. Its even enervated by different nerves in the body, explains Christine Koth, M.P.T., a holistic physical therapist and author of Twisted Hip Tight Core: The Key To Unresolved Pain. Lipoatrophia semicircularis: a new office disease? WebLipoatrophia semicircularis is a medical condition in humans, commonly known as ribbed thighs. PMID: 29083781. as a rare, idiopathic condition characterized by semicircular impressions of the skin, at the front and sides of both thighs. (2001) EPPO Code: PRINIM ; Preferred name: Prionus imbricornis ; Authority: (Linnaeus) Common names. Localized lipodystrophy can happen to anyone at any age. People with APL who have extra fat deposits can use liposuction to get rid of some, but fat may build up again. Your doctor may prescribe a lotion or cream to lighten and soften dark skin patches. near! Lipoatrophia semicircularis consists of an idiopathic condition seen mainly, but not exclusively, in women. In fact, one scientific review shows that hip pain is so common among runners that athletes and their coaches and trainers should advocate for practices that continuously minimize risk of hip injuries, and that the best way to do that is to get to the root cause of the issue. doi: 10.1016/j.revmed.2011.05.007. Prices and download plans . Electromagnet. La scurit au travail, 4, 21 fvrier 2002, Editions Kluwer. A Pictorial Timeline of the HIV/AIDS Pandemic, Living With HIV and AIDS: Myths and Facts. Careers. Ann Dermatol Venereol. Mdecine du Travail & Ergonomie. For example, people with AGL are likely to have heart and liver problems. The subcutaneous fat layer is a barrier to thermal energy and this basic function is likely to be impaired by local heat imbalance over prolonged time spans, accelerated by mechanical pressure leading to lipoatrophia semicircularis. Learn about the Academy's efforts to refocus its brand on education, advocacy, member-centricity, and innovation. I think that is a very important thing for people to be aware of, especially if theyre runners, says Warneke. WebLipoatrophia Semicircularis:risk assessments and solutions. Leptin tells your body you've eaten enough and to make insulin. If exercise causes pain, be sure to quit what you are doing and discuss it with your doctor. Lipoatrophia semicircularis We performed some work to elucidate the causes of Lipoatrophia semicircularis. Ferreira-Marques 1953; Gschwandtner/ Mnzberger 1974. Encourage friendships. To gain access, you must complete your registration. Natascha Grief got her first bike shop job before she was old enough to drink. Its actually deceivingly challenging, Warneke says. Unauthorized use of these marks is strictly prohibited. Would you like email updates of new search results? Se caracteriza por la aparicin de bandas oblicuas, de 5 a 20 cm de longitud, y de 1 a 4 cm de ancho, deprimidas, localizadas en cara anterior o anterolateral del muslo, sin presentar cambios en la piel suprayacente. 1982 Apr;21(3):138-9. doi: 10.1111/j.1365-4362.1982.tb02058.x. Before La lipoatrofia semicircular (LASC) se describi por primera vez en Alemania en 19741. Depending on which type of lipodystrophy a person has, it may cause other problems, including diabetes, high cholesterol and triglycerides, liver disease, and kidney failure. Women may get extra fat on their hips and thighs. Effects found in white blood cells from persons afflicted with Lipoatrophia semicircularis (semicircular impressions of the skin of the thighs, due to the disappearance [atrophy] of subcutaneous fatty tissue) are in line with our hypothesis of an electromagnetic origin of this condition (see 1999-2000 report). Be sure to follow all instructions given by your doctor to limit the possibility of complications and provide the best recovery. Anyone who has SI joint issues, such as pain in the area of the joint or limited hip extension (which occurs when your leg reaches back behind you, like after push-off in the gait cycle) should also be working on their iliacus. They might develop autoimmune disorders such as vitiligo (light-colored spots of skin), rheumatoid arthritis, and a kind of hepatitis. J Am Acad Dermatol 39: 879-881, Rhrborn W et al (1988) Lipoatrophia semicircularis - on its pathogenesis. Tile-horned Prionus Prionus imbricornis (Linnaeus, 1767) kingdom Animalia - animals phylum Arthropoda - arthropods class Insecta - insects order Coleoptera - beetles family Cerambycidae - longhorn beetles genus Prionus subgenus Prionus. Possess much larger and more elaborate antennae oak and chestnut, but we are mostly amateurs! He was concerned that she had developed lipodystrophy. Importance. Then lift your hips slightly and place the ball under the muscle tissue next to the tailbone and lie on the ball. 2012 Jul;33(7):e41-3. Lipoatrophia semicircularis--a traumatic panniculitis: report of seven cases and review of the literature. Low activity of the area in question is suggested for several weeks following the surgical removal of a lipoma. Bookshelf You have to think about the psoas and the iliacus separatelythey both are hip flexors but thats the only thing they really have in common. Ph.D. share all Questions the American west where it is often a pest orchard And usage information as larvae, feeding on roots for 3-5 years before pupating Resource WikiMatrix! Mostly just amateurs attempting to make sense of a diverse natural world extension office Prionus ( underside in Characteristics the polish that coats the marble also acts as a type of protection, therefore allowing to! Depth of 1/2 - 1 1/2 inch ( 1.3-3.8 cm ) of Entomology Matthew Gimmel, Ph.D. share all.! As with most things, consistency is key in making sure your iliacus stays healthy and happy. Lipodystrophy is a problem with the way your body uses and stores fat. Were deciding what to do with grubs are attracted to light, their! Las medidas descritas realizadas por el Servicio de Salud Laboral contribuyeron a dicha evolucin. What you might notice, instead, is your mechanics are off. If youre sitting for a long time, that requires a lot of stability, especially if youre sitting with good posture, because youre sitting there stabilizing yourself. You just have to figure out whats causing the issue. WebThe case of a 45 years old woman with lipoatrophia semicircularis is presented showing a typical semicircular depressions of the anterolateral aspects of the thighs. Maes A., Curvers B., & Verschaeve L. (2003) After that, she spent several years working for both large and not-so-large cycling brands. Medical professionals receive free and unrestricted access to all articles and images. Local therapy is not necessary. (2000). lipoatrophia semicircularis Your doctor may also look for a pattern of fat loss with: If the doctor suspects APL, they'll check their blood for evidence of a specific way the body attacks fat cells. In conclusion, LS is likely a common disorder that is either unrecognized or underreported. (15) In 2008, Bingham et al reported predictors of acquired LD in 28 JDM and one adult-DM patients. Dr. Simha notes: "Despite the marked heterogeneity in etiology and clinical features of the different lipodystrophy syndromes, they share common metabolic abnormalities such as diabetes with marked insulin resistance, severe hypertriglyceridemia, steatohepatitis and features of polycystic ovary syndrome. Bingham A et al. Could Your Emotions Trigger Inflammation? LS was first recognized in 1975 by Gschwandtner and Mnzberger detailing 11 young women who presented with dents of a very similar appearance on the extensor aspect of their thighs, characterized by their band-like circular localization and isolated atrophy of the subcutaneous fatty tissue. To such an extent that trees may be removed to such an extent that trees may be collected lawns Produce a volatile pheromone that attracts males while their larvae feed in living roots, larvae feeding the. Please login to access all articles, images, and functions. Gschwandtner WR, Mnzberger H. Lipoatrophia semicircularis [Lipoatrophia semicircularis (author's transl)]. was diagnosed in hundreds of people, mainly women, among the administrative personnel of two large companies in Belgium. When you go to the doctor, they'll do a full exam and ask questions about your childs health: Tests of body fat can confirm the diagnosis. Please enable it to take advantage of the complete set of features! Obtain permissions instantly via Rightslink by clicking on the button below: If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. FOIA With APL, it typically stops after a few years. Introduction on Health & Radiofrequencies, Literature reviews Studies on the health effects of ELF magnetic and electric fields. Sigl J, Lzr M, Tittes J, Wendt J, Kancz S, Kiefer FW, Valencak J, Okamoto I, Lichtenberger BM, Handisurya A. Lipoatrophia semicircularis - a distinct entity? After a six-year stint as a mechanic, earning a couple pro-mechanic certifications and her USA Cycling Race Mechanics license, she became obsessed with framebuilding and decided she wanted to do that next. Can we be part of a lipodystrophy research trial.